Dexamethasone

1. Basic Information. 1.1. Synonym:9α-Fluoro-16α-methylprednisolone, Prednisolone F, (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione ; 1.2. CAS Number: 50-02-2; 1.3. Linear Formula: C22H29FO5 1.4. Molecular Weight: 392.46; 1.5. Beilstein Registry Number: 2066651; 1.6. EC Number: 200-003-9; 1.7. MDL number: MFCD00064136; 1.8. PubChem Substance ID: 24893536; 1.9. Function / Clasification: Intermediate, Anti inflammatory 2. Description. 2.1 Biochem/physiol Actions: Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase. 2.2 Reconstitution: Dilute 1 mg/ml stock solution 1:50 with sterile media and store frozen in working aliquots to avoid repeated freeze-thaw. 3. Properties. 3.1 assay: ≥98% (HPLC) 3.2 form: powder; 3.3 color: off-white; 3.4 mp: 262 264 degree Celsius; 3.5 solubility: ethanol: soluble1 mg/mL; 3.6 storage temp.: 2-8°C 4. Safety. 4.1 Personal Protective Equipment: dust musk type N95 (US); Eyeshields; Faceshields, Gloves; 4.2 Harzard Codes: Xi;